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Are you also trapped in the cycle of "blushing" anxiety? During the meeting presentation, your cheeks steal the spotlight more than the PPT. When exposed to alternating hot and cold temperatures, your skin instantly turns into a "red apple". Facial redness is like a sudden storm that sweeps in without warning, catching you off guard. Given the widespread issues related to facial redness, JAKA's new soothing ingredient offers a new solution for you. Erythcalm SC is an oil-soluble ingredient with redness-reducing properties. It is extracted from the traditional Chinese herbal medicine Saururus chinensis and is COSMOS APPROVED. The occurrence of skin erythema can be attributed to the localized and sustained increase in blood flow caused by various triggers, and it can also result from the extravasation of red blood cells from blood vessels and their deposition in the skin. JAKA has comprehensively analyzed irritants that could potentially cause skin redness. Different skin receptors were activated using various irritants, which subsequently induced the activation of signaling pathways, leading to issues such as redness, pain, and itchiness. Then, JAKA adopted a "4-Tier Model" to mimic redness condition. This model covers contact irritation, allergic irritation, temperature-induced irritation, and stress-induced redness. Additionally, Erythcalm SC innovatively targets and regulates EDNRA and ADRB2 receptors, and comprehensively constructs overexpressed cell lines to highly replicate the cellular response process after skin irritation. Ex vivo skin tests have verified the inhibitory effect of Erythcalm SC on CGRP production. CGRP is an important neuropeptide expressed in various human cells and has multiple physiological functions, mainly including vasodilation to promote inflammation, regulating neuronal sensitization, and causing pain. The results show that Erythcalm SC can dose-dependently inhibit the production of CGRP induced by methyl nicotinate and ISO in ex vivo skin.
Clinical tests show that with just 0.5% dosage level, Erythcalm SC can rapidly soothe skin redness caused by various irritants (such as histamine and methyl nicotinate) within 15 min.
Moreover, JAKA conducted multi-efficacy tests on facial skin. The results show that after 28 days of using 2% Erythcalm SC, there were significant improvements in three indicators: moisture content, skin gloss, and L-value. From this, it can be concluded that 2% Erythcalm SC has certain moisturizing and brightening effects.
Erythcalm SC has a mild odor, excellent stability, and good compatibility with common oils in formulations, allowing for wide applications in various oil-based and cream-based formulas. Its application scenarios are also extensive. It can be used in soothing and redness-relieving products, as well as in body care or spot care products, such as bath oils and cuticle oils. Additionally, it can be added to color cosmetics products, combining makeup and skincare to minimize irritation. To sum up, if you are looking for an oil-soluble ingredient with redness-reducing properties, it is a good choice to consider.